Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.37 |
| ▸ | PPARA | Q07869 | 9/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923042 | 0.90 | PPARG (0.38) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL8925292 | 0.82 | PPARG (0.39) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL8923313 | 0.76 | FNTA (0.40) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA7 | |
| SCHEMBL8992166 | 0.75 | ACP3 (0.48) | CYP2C19HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL8925299 | 0.72 | PPARG (0.40) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL9348895 | 0.69 | CYP2C19 (0.42) | PPARGCYP2C19PPARD | |
| SCHEMBL9348901 | 0.69 | CYP4F2 (0.44) | PPARGPPARAHPGD | |
| SCHEMBL29866205 | 0.65 | CA12 (0.50) | HDAC8HDAC6KDM4EALDH1A1GAA | |
| SCHEMBL2010178 | 0.65 | CA12 (0.50) | HDAC8HDAC6KDM4EALDH1A1GAA | |
| SCHEMBL8992172 | 0.65 | PGK1 (0.53) | CYP2C19HDAC8HDAC6MCL1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |