Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.53 |
| ▸ | PGK2 | P07205 | 3/20 | 0.53 |
| ▸ | ACP3 | P15309 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992166 | 0.84 | ACP3 (0.48) | PGK1PGK2ACP3MEN1ALOX15 | |
| SCHEMBL8923313 | 0.79 | FNTA (0.40) | TDP1HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL8992581 | 0.78 | PGK1 (0.56) | PGK1PGK2HSD17B10 | |
| SCHEMBL30545233 | 0.77 | ENPP3 (0.47) | HSD17B10HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL838870 | 0.77 | ENPP3 (0.47) | HSD17B10HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL30545232 | 0.77 | MEN1 (0.72) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL838874 | 0.77 | MEN1 (0.72) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| Phosphine SCHEMBL28240948 | 0.76 | ENPP3 (0.46) | HSD17B10HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL8925299 | 0.75 | PPARG (0.40) | CYP2C19TDP1HDAC8HDAC6MCL1 | |
| SCHEMBL8992302 | 0.74 | PTPN5 (0.41) | PGK1PGK2ACP3CYP2C19HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | disclosed |