Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698309 | 0.83 | BRD9 (0.38) | TACR1ALDH1A1IDH1BRD9BRD7 | |
| SCHEMBL838870 | 0.83 | ENPP3 (0.47) | FNTAFNTBENPP3ENPP1CYP2A6 | |
| SCHEMBL30545233 | 0.83 | ENPP3 (0.47) | FNTAFNTBENPP3ENPP1CYP2A6 | |
| Phosphine SCHEMBL28240948 | 0.81 | ENPP3 (0.46) | FNTAFNTBENPP3ENPP1CYP2A6 | |
| SCHEMBL12698310 | 0.81 | PDCD1 (0.37) | ALDH1A1IDH1CA12CA1CA2 | |
| SCHEMBL22515944 | 0.79 | ENPP3 (0.42) | FNTAFNTBENPP3ENPP1CYP2A6 | |
| SCHEMBL8992172 | 0.79 | PGK1 (0.53) | MCL1ACMSDIDH1TDP1HDAC8 | |
| SCHEMBL27454841 | 0.77 | CA12 (0.45) | FNTAFNTBENPP3ENPP1CYP2A6 | |
| SCHEMBL8992166 | 0.76 | ACP3 (0.48) | MCL1ACMSDTDP1HDAC8HDAC6 | |
| SCHEMBL15856458 | 0.76 | ENPP3 (0.42) | FNTAFNTBENPP3ENPP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | claimed |
| US-5668121-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | disclosed |