SCHEMBL8923065

SCHEMBL8923065

CCCCCCCCc1c(Cl)ccc(C(=O)O)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.50
RARB P10826 7/20 0.49
PPARG P37231 1/20 0.47
KAT8 Q9H7Z6 2/20 0.47
RARA P10276 2/20 0.46
RARG P13631 1/20 0.46
PLK1 P53350 5/20 0.44
PLK3 Q9H4B4 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
MTOR P42345 1/20 0.42
KMT2A Q03164 1/20 0.42
GPR35 Q9HC97 1/20 0.42
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514918 1.00 PPARA (0.50) PPARARARBPPARGKAT8RARA
SCHEMBL9706039 1.00 PPARA (0.50) PPARARARBPPARGKAT8RARA
SCHEMBL8924183 0.92 F7 (0.47) PPARARARBPPARGALDH1A1MAPT
SCHEMBL8924429 0.87 TSHR (0.44) PPARAMEN1ALDH1A1KMT2AAKR1C2
SCHEMBL5710024 0.85 PPARA (0.48) PPARARARBPPARGKAT8RARA
SCHEMBL10416283 0.82 PPARA (0.48) PPARARARBPPARGKAT8RARA
SCHEMBL5915272 0.82 PPARA (0.48) PPARARARBPPARGKAT8RARA
SCHEMBL5915245 0.82 PPARA (0.48) PPARARARBPPARGKAT8RARA
SCHEMBL8660552 0.81 ALDH1A1 (0.49) ALDH1A1MAPTKMT2A
SCHEMBL14836066 0.81 PPARA (0.60) PPARARARBPPARGKAT8RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688959-A MULTICOLOR DYE IMAGE AND INFRARED RADIATION ABSORBER WITH 1-HYDROXY-2-N-(5-ALKYLTHIAZOL-2-YL)NAPHTHAMIDE COUPLERS FORMING QUINONE IMINE DYES AGFA-GEVAERT, N.V. (BE) 1997-11-18 US disclosed
US-5030544-A 1-hydroxy-2-n(5-alkyl thiazol 2-yl) naphthamides, form quinone-imine dyes AGFA-GEVAERT, N.V. (BE) 1991-07-09 US disclosed
EP-0176628-B1 PHOTOGRAPHIC COLOUR ELEMENTS AGFA-GEVAERT N.V. (BE) 1987-11-25 EP disclosed
EP-0084692-B1 METHOD OF DISPERSING PHOTOGRAPHIC ADJUVANTS IN A HYDROPHILIC COLLOID COMPOSITION AGFA-GEVAERT N.V. (BE) 1986-06-11 EP disclosed
EP-0176628-A1 Photographic colour elements AGFA-GEVAERT N.V. (BE) 1986-04-09 EP disclosed
US-4430421-A USING IHYDROXYMETHYL(5,2,1,0(2,6))TRICYCLODECANE, OR CARBOXYLIC, PHOSPHORIC, OR PHOSPHONIC DIESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
US-4430422-A USING 1,3-DIALKYLOXY-2-PROPANOLS AND CARBOXYLIC, PHOSPHORIC OR PHOSPHONIC ESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
EP-0084694-A1 Method of dispersing photographic adjuvants in hydrophilic colloid compositions AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
EP-0084692-A2 Method of dispersing photographic adjuvants in a hydrophilic colloid composition AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed