SCHEMBL8924183

SCHEMBL8924183

CCCCCCCCC=CCCCCCCCCc1c(Cl)ccc(C(=O)O)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 6/20 0.47
F3 P13726 6/20 0.47
MMP2 P08253 3/20 0.47
ALOX15 P16050 3/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
ECE1 P42892 1/20 0.47
SGMS1 Q86VZ5 1/20 0.47
SGMS2 Q8NHU3 1/20 0.47
MUS81 Q96NY9 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
EPHX2 P34913 1/20 0.46
BID P55957 3/20 0.44
BCL2L1 Q07817 3/20 0.44
MCL1 Q07820 3/20 0.44
BAK1 Q16611 3/20 0.44
PPARA Q07869 3/20 0.44
RARB P10826 1/20 0.43
ALDH1A1 P00352 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706039 0.92 PPARA (0.50) MAPTPPARARARBALDH1A1PPARG
SCHEMBL8923065 0.92 PPARA (0.50) MAPTPPARARARBALDH1A1PPARG
SCHEMBL7514918 0.92 PPARA (0.50) MAPTPPARARARBALDH1A1PPARG
SCHEMBL8924429 0.80 TSHR (0.44) KDM4EMCL1PPARAALDH1A1LMNA
SCHEMBL8924179 0.80 FAAH (0.47) F7F3MMP2ALOX15HSD17B10
SCHEMBL5710024 0.78 PPARA (0.48) PPARARARBPPARG
SCHEMBL17080352 0.76 F7 (0.60) F7F3MMP2ALOX15HSD17B10
SCHEMBL17080353 0.76 F7 (0.60) F7F3MMP2ALOX15HSD17B10
SCHEMBL10416283 0.75 PPARA (0.48) MAPTPPARARARBALDH1A1PPARG
SCHEMBL5915245 0.75 PPARA (0.48) MAPTPPARARARBALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688959-A MULTICOLOR DYE IMAGE AND INFRARED RADIATION ABSORBER WITH 1-HYDROXY-2-N-(5-ALKYLTHIAZOL-2-YL)NAPHTHAMIDE COUPLERS FORMING QUINONE IMINE DYES AGFA-GEVAERT, N.V. (BE) 1997-11-18 US disclosed
US-5030544-A 1-hydroxy-2-n(5-alkyl thiazol 2-yl) naphthamides, form quinone-imine dyes AGFA-GEVAERT, N.V. (BE) 1991-07-09 US disclosed
EP-0084692-B1 METHOD OF DISPERSING PHOTOGRAPHIC ADJUVANTS IN A HYDROPHILIC COLLOID COMPOSITION AGFA-GEVAERT N.V. (BE) 1986-06-11 EP disclosed
EP-0176628-A1 Photographic colour elements AGFA-GEVAERT N.V. (BE) 1986-04-09 EP disclosed
US-4430422-A USING 1,3-DIALKYLOXY-2-PROPANOLS AND CARBOXYLIC, PHOSPHORIC OR PHOSPHONIC ESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
US-4430421-A USING IHYDROXYMETHYL(5,2,1,0(2,6))TRICYCLODECANE, OR CARBOXYLIC, PHOSPHORIC, OR PHOSPHONIC DIESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
EP-0084694-A1 Method of dispersing photographic adjuvants in hydrophilic colloid compositions AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
EP-0084692-A2 Method of dispersing photographic adjuvants in a hydrophilic colloid composition AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed