Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118331 | 0.88 | SCN9A (0.44) | SCN9ATDP1SCN5AMEN1TTR | |
| SCHEMBL11365028 | 0.87 | TDP1 (0.39) | SCN9ATDP1MEN1TTRPPOX | |
| SCHEMBL11213666 | 0.85 | TDP1 (0.57) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11190333 | 0.84 | TDP1 (0.43) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9120594 | 0.84 | MEN1 (0.52) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10430085 | 0.83 | TDP1 (0.43) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10663135 | 0.82 | TDP1 (0.41) | SCN9ATDP1SCN5AMEN1TTR | |
| SCHEMBL10495360 | 0.82 | TDP1 (0.41) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10672572 | 0.81 | TDP1 (0.53) | SCN9ATDP1MEN1TTRPPOX | |
| SCHEMBL11354485 | 0.81 | SCN9A (0.48) | SCN9ATDP1SCN5AMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593942-A | MIXTURES OF HERBICIDES WITH SYNERGISTIC COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0186989-B1 | 5-(2-CHLORO-4-TRIFLUOROMETHYLPHENOXY)-2-NITRO-ALPHA-SUBSTITUTED-ACETOPHENONE, OXIME DERIVATIVE THEREOF, PROCESS FOR PREPARING THEREOF, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-09-26 | — | — | EP | disclosed |