Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | PPOX | P50336 | 1/20 | 0.52 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190333 | 0.91 | TDP1 (0.43) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10430085 | 0.90 | TDP1 (0.43) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11213666 | 0.89 | TDP1 (0.57) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11107822 | 0.89 | TDP1 (0.47) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10495360 | 0.88 | TDP1 (0.41) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11114839 | 0.87 | TDP1 (0.45) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11266141 | 0.87 | TDP1 (0.45) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11287905 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10947425 | 0.85 | GPR35 (0.39) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10766268 | 0.84 | TDP1 (0.42) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474974-A | Insecticide, pesticide, nematocide, miticide and herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5332720-A | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| US-4435588-A | 2'-CHLORO-4'-TRIFLUOROMETHYL-PHENOXY-3-BENZOATE DERIVATIVES | GAF CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0019388-A1 | Preparation of trifluoromethyl-substituted phenols and phenates and the preparation, from these phenols and phenates, of nitro- and trifluoromethyl-substituted diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-11-26 | — | — | EP | disclosed |