Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120594 | 0.91 | MEN1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10430085 | 0.90 | TDP1 (0.43) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11213666 | 0.89 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10495360 | 0.88 | TDP1 (0.41) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11114839 | 0.87 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11266141 | 0.87 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11287905 | 0.86 | ALDH1A1 (0.46) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10947425 | 0.85 | GPR35 (0.39) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10766268 | 0.84 | TDP1 (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL8923180 | 0.84 | SCN9A (0.43) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072649-A2 | Novel substituted diphenyl ethers, herbicidal compositions containing them, a process for the preparation of the diphenyl ethers and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| EP-0066989-A2 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, a process for the preparation of the nitrodiphenyl ethers and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| EP-0066106-A1 | New phenoxybenzoates, process for preparing these compounds, compositions containing them and method of use | GAF CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |