⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961620 | 1.00 | — | — | |
| SCHEMBL11242319 | 0.80 | — | — | |
| SCHEMBL11242326 | 0.80 | — | — | |
| SCHEMBL221551 | 0.78 | — | — | |
| SCHEMBL221550 | 0.78 | — | — | |
| SCHEMBL13324416 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL222772 | 0.76 | GLO1 (0.50) | — | |
| SCHEMBL3384361 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL19447665 | 0.76 | GLO1 (0.50) | — | |
| SCHEMBL322511 | 0.76 | GLO1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |