SCHEMBL8923255

SCHEMBL8923255

CC[CH]C(C)Oc1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
SIGMAR1 Q99720 4/20 0.39
P2RX3 P56373 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
PPARG P37231 4/20 0.38
PPARA Q07869 4/20 0.38
GAA P10253 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
SLC6A4 P31645 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923706 0.85 PPARA (0.39) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL8923939 0.81 ALDH1A1 (0.41) CYP1A2CYP2C19L3MBTL1PPARGPPARA
SCHEMBL8925963 0.81 MAPT (0.35)
SCHEMBL9316517 0.80 MTNR1A (0.40) POLBCYP1A2CYP2C9CYP2C19SIGMAR1
SCHEMBL8995787 0.78 POLB (0.44) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL18321308 0.76 CYP1A2 (0.46) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL97276 0.76 CYP1A2 (0.46) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL8925878 0.75 SMN1; SMN2 (0.51) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL9191274 0.74 SIGMAR1 (0.49) POLBCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL11515268 0.73 CYP1A2 (0.44) POLBCYP1A2CYP2C9CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677263-A CONTROLLING UNWANTED GRASSES BASF AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5523462-A HERBICIDES; PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed