Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847371 | 0.92 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7847367 | 0.92 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9211202 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7847782 | 0.91 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7843329 | 0.90 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7834705 | 0.89 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7844361 | 0.89 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924069 | 0.88 | LMNA (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7847276 | 0.87 | KCNH2 (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7501715 | 0.87 | KCNH2 (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621105-A | REACTING HALO-SUBSTITUTED QUINOLONECARBOXYLIC ACID OR NAPHTHYRIDONECARBOXYLIC ACID WITH 1-AMINOMETHYL-2-OXA-7-AZABICYCLO/3.3.0/OCTANE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5574161-A | GRAMPOSITIVE BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395944-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |