Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461518 | 0.88 | P2RY12 (0.48) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL3822223 | 0.88 | P2RY12 (0.48) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL3822219 | 0.88 | P2RY12 (0.48) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL9650579 | 0.83 | P2RY12 (0.50) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL9650582 | 0.83 | P2RY12 (0.50) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL9651474 | 0.83 | P2RY12 (0.50) | P2RY12TYMPADORA3P2RY2P2RY1 | |
| SCHEMBL25504687 | 0.83 | ADORA3 (0.52) | P2RY12ADORA3SLC29A1 | |
| SCHEMBL25505312 | 0.83 | ADORA3 (0.52) | P2RY12ADORA3SLC29A1 | |
| SCHEMBL25969465 | 0.83 | ADORA3 (0.52) | P2RY12ADORA3SLC29A1 | |
| SCHEMBL13374198 | 0.83 | ADORA3 (0.52) | P2RY12ADORA3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |