Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.48 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822219 | 1.00 | P2RY12 (0.48) | P2RY12TYMPADORA3P2RY1P2RY2 | |
| SCHEMBL29461518 | 1.00 | P2RY12 (0.48) | P2RY12TYMPADORA3P2RY1P2RY2 | |
| SCHEMBL19519463 | 0.91 | P2RY12 (0.43) | P2RY12ADORA3P2RY1P2RY2P2RY6 | |
| SCHEMBL17283107 | 0.91 | P2RY12 (0.43) | P2RY12ADORA3P2RY1P2RY2P2RY6 | |
| SCHEMBL30197028 | 0.91 | P2RY12 (0.43) | P2RY12P2RY1P2RY2P2RY6 | |
| SCHEMBL24823137 | 0.88 | P2RY12 (0.42) | P2RY12P2RY1P2RY2P2RY6 | |
| SCHEMBL8923624 | 0.88 | P2RY12 (0.45) | P2RY12TYMPADORA3P2RY1P2RY2 | |
| SCHEMBL31195761 | 0.88 | P2RY12 (0.42) | P2RY12P2RY1P2RY2P2RY6 | |
| SCHEMBL17283109 | 0.88 | P2RY12 (0.43) | P2RY12P2RY1P2RY2P2RY6 | |
| SCHEMBL19519464 | 0.88 | P2RY12 (0.43) | P2RY12P2RY1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230160000-A1 | SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230160000-A1 | SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230028388-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | disclosed |
| US-11548910-B2 | Oligonucleotide production method | NISSAN CHEMICAL CORPORATION (JP) | 2023-01-10 | — | — | US | disclosed |
| US-20220411860-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-12-29 | — | — | US | disclosed |
| US-11390858-B2 | Modified template-independent enzymes for polydeoxynucleotide synthesis | Molecular Assemblies, Inc. (US) | 2022-07-19 | — | — | US | disclosed |
| US-11085076-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-03-05 | — | — | US | disclosed |
| EP-1253154-B1 | Method for purifying 5'-protected 2'-deoxypurine nucleosides | MITSUI CHEMICALS INC (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-7074917-B2 | Method for purifying 5′ -protected 2′ -deoxypurine nucleosides | MITSUI CHEMICALS, INC. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20060009635-A1 | Method for purifying 5' -protected 2' -deoxypurine nucleosides | MITSUI CHEMICALS, INC. (JP) | 2006-01-12 | — | — | US | disclosed |
| US-6958391-B2 | Method for purifying 5′-protected 2′-deoxypurine nucleosides | MITSUI CHEMICALS, INC. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030009028-A1 | Method for purifying 5' -protected 2' -deoxypurine nucleosides | MITSUI CHEMICALS, INC. (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1253154-A1 | Method for purifying 5'-protected 2'-deoxypurine nucleosides | Mitsui Chemicals, Inc. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009028-A1 | Method for purifying 5' -protected 2' -deoxypurine nucleosides | PNP, UMPS, NT5C3B | P2RY12 1324/4885TYMP 8/4885ADORA3 1123/4885 |
| US-20220411860-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | POLL, POLQ, POLB | P2RY12 4463/4885TYMP 38/4885ADORA3 3709/4885 |
| US-20060009635-A1 | Method for purifying 5' -protected 2' -deoxypurine nucleosides | PNP, UMPS, NUDT1 | P2RY12 1247/4885TYMP 7/4885ADORA3 897/4885 |
| US-20230028388-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | RNGTT, POLRMT, MTR | P2RY12 4423/4885TYMP 63/4885ADORA3 2497/4885 |
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, RNGTT | P2RY12 2675/4885TYMP 36/4885ADORA3 248/4885 |
| US-11085076-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | POLRMT, RNGTT, MTR | P2RY12 4600/4885TYMP 89/4885ADORA3 3497/4885 |
| US-11548910-B2 | Oligonucleotide production method | RNGTT, OSGEP, PHAX | P2RY12 1735/4885TYMP 18/4885ADORA3 644/4885 |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, NUDT1 | P2RY12 2098/4885TYMP 34/4885ADORA3 214/4885 |
| US-20230160000-A1 | SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | POLRMT, RNGTT, MTR | P2RY12 4600/4885TYMP 89/4885ADORA3 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.