Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650786 | 0.86 | SIRT1 (0.53) | ALDH1A1KDM4EL3MBTL1HPGDMAPK1 | |
| SCHEMBL1482567 | 0.75 | POLB (0.74) | POLBPKMCA12CA1CA2 | |
| SCHEMBL29888792 | 0.75 | POLB (0.74) | POLBPKMCA12CA1CA2 | |
| SCHEMBL1581304 | 0.74 | POLB (0.47) | POLBPKMCA12CA1CA2 | |
| SCHEMBL9460748 | 0.73 | POLB (0.71) | POLBPKMCA12CA1CA2 | |
| SCHEMBL231042 | 0.70 | SIRT1 (0.71) | POLBPKMCA12CA1CA2 | |
| SCHEMBL14891741 | 0.70 | FLT3 (0.47) | POLBCA12CA1CA2CA4 | |
| SCHEMBL10830149 | 0.70 | NPC1 (0.61) | POLBRAB9ACYP1A2ALDH1A1TDP1 | |
| SCHEMBL126695 | 0.69 | POLB (0.59) | POLBPKMCA12CA1CA2 | |
| SCHEMBL11614461 | 0.69 | RAB9A (0.49) | POLBCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665830-A | POLYOXYETHYLENE OXIDE | HERCULES INCORPORATED (US) | 1997-09-09 | — | — | US | disclosed |