Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824479 | 0.81 | GAA (0.38) | RAB9AGAANPC1CYP3A4CYP2D6 | |
| SCHEMBL8992145 | 0.81 | GAA (0.41) | CYP1A2RAB9AGAANPC1LMNA | |
| SCHEMBL8921403 | 0.80 | RAB9A (0.40) | HRH1SMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL8924199 | 0.79 | SCN8A (0.46) | SCN8AHRH1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8824453 | 0.79 | GAA (0.36) | RAB9AGAANPC1LMNATP53 | |
| SCHEMBL8824463 | 0.76 | MAPT (0.40) | SMN1; SMN2CYP1A2CYP2C19RAB9AGAA | |
| SCHEMBL8558817 | 0.76 | GAA (0.35) | RAB9AGAANPC1CYP3A4CYP2D6 | |
| SCHEMBL8663366 | 0.74 | SCN8A (0.47) | SCN8AHRH1SMN1; SMN2CA12CA1 | |
| SCHEMBL9090606 | 0.73 | GAA (0.35) | RAB9AGAANPC1CYP3A4CYP2D6 | |
| SCHEMBL6981958 | 0.73 | RAB9A (0.35) | HRH1SMN1; SMN2RAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |