Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22939095 | 0.90 | SELL (0.67) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| Phthalic Acid SCHEMBL28580253 | 0.87 | ALDH1A1 (0.70) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| Phthalic Acid SCHEMBL28580250 | 0.87 | ALDH1A1 (0.70) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| SCHEMBL245254 | 0.87 | FNTA (0.58) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| SCHEMBL9686287 | 0.85 | SELL (0.66) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| SCHEMBL1334176 | 0.85 | ALDH1A1 (0.74) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| SCHEMBL30740067 | 0.85 | LIG1 (0.55) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| SCHEMBL301928 | 0.85 | LIG1 (0.55) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL10534711 | 0.85 | ALDH1A1 (0.67) | KMT2ACYP3A4CYP2C9ALDH1A1CA12 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL37458 | 0.85 | SELL (0.70) | KMT2AALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | THE UNIVERSITY OF CHICAGO (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
| US-5637733-A | Syntheses of fluorescein compounds with excess resorcinol as a solvent | WARNER-JENKINSON COMPANY, INC. (US) | 1997-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | DNPEP, PTMS, CTH | KMT2A 3156/4885CYP3A4 418/4885CYP2C9 526/4885 |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | DNPEP, PTMS, CTH | KMT2A 3156/4885CYP3A4 418/4885CYP2C9 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.