Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 4/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923952 | 1.00 | NT5E (0.62) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL26291351 | 1.00 | NT5E (0.62) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL13890093 | 0.90 | AHCY (0.54) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL8620311 | 0.90 | AHCY (0.54) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL13873163 | 0.90 | AHCY (0.54) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL8620317 | 0.90 | AHCY (0.54) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL13713932 | 0.90 | AHCY (0.54) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL3036906 | 0.89 | LMNA (0.65) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL3036901 | 0.89 | LMNA (0.65) | NT5ELMNAHIF1AAHCYADORA2A | |
| SCHEMBL21132768 | 0.89 | LMNA (0.65) | NT5ELMNAHIF1AAHCYADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661136-A | 2-halo-2'-fluoro ARA adenosines as antinoplastic agents | SOUTHERN RESEARCH INSTITUTE (US) | 1997-08-26 | — | — | US | disclosed |
| US-5384310-A | Antitumor | SOUTHERN RESEARCH INSTITUTE (US) | 1995-01-24 | — | — | US | disclosed |