Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695032 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8694255 | 0.92 | CCR5 (0.33) | ALDH1A1MAPTCCR5GAADPP8 | |
| SCHEMBL10699990 | 0.92 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2ACCR5HPGD | |
| SCHEMBL9519504 | 0.92 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2ACCR5HPGD | |
| SCHEMBL8694956 | 0.89 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9390647 | 0.89 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8925234 | 0.88 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL8691045 | 0.88 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL8924394 | 0.86 | HTR2A (0.34) | ALDH1A1MAPTCCR5GAADPP8 | |
| SCHEMBL8694261 | 0.86 | HTR2A (0.34) | ALDH1A1MAPTCCR5GAADPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| EP-0674640-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP (KR) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |