Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694261 | 1.00 | HTR2A (0.34) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8924036 | 0.90 | TDP1 (0.34) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8689891 | 0.90 | TDP1 (0.34) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL9388494 | 0.89 | HTR2A (0.37) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8690852 | 0.89 | HTR2A (0.37) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8694762 | 0.88 | HTR2A (0.37) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8924002 | 0.86 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL8695032 | 0.86 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL8694624 | 0.86 | ALDH1A1 (0.35) | HTR2ADPP8DPP9MMP2MMP9 | |
| SCHEMBL8923764 | 0.86 | ALDH1A1 (0.35) | HTR2ADPP8DPP9MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |