SCHEMBL8924023

SCHEMBL8924023

CCOC(=O)C(C)(C)Oc1ccc(CCOc2cc(C)c(OC(C)=O)c(C)c2C)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.46
ABCB11 O95342 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
HTR2A P28223 1/20 0.46
PMP22 Q01453 1/20 0.46
PPARG P37231 13/20 0.45
PPARD Q03181 12/20 0.45
FBP1 P09467 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767488 0.89 PPARA (0.57) PPARAPPARGPPARD
SCHEMBL8616248 0.85 PPARG (0.38) PPARACYP1A2TSHRPPARGPPARD
SCHEMBL8050816 0.78 PPARA (0.48) PPARACYP1A2TSHRPPARGPPARD
SCHEMBL8768731 0.74 PPARA (0.62) PPARAPPARGPPARD
SCHEMBL14584455 0.73 PPARG (0.61) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL3341525 0.72 PPARA (0.68) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL14584452 0.72 PPARA (0.56) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL3692605 0.71 PPARA (0.65) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL1349983 0.71 PPARA (0.64) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL1550078 0.71 PPARA (0.64) PPARAABCB11CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed
US-5512595-A FOR SUPPRESSION OF MEMBRANE LIPID PEROXIDATION, ANTILIPEMIC AGENTS ADIR ET COMPAGNIE (FR) 1996-04-30 US disclosed