Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616248 | 0.89 | PPARG (0.38) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8616686 | 0.86 | PPARA (0.51) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8767488 | 0.84 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL8051214 | 0.82 | PPARA (0.51) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL11095485 | 0.78 | PPARA (0.62) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8617631 | 0.78 | PPARA (0.56) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8924023 | 0.78 | PPARA (0.46) | PPARAPPARGCYP1A2TSHRPPARD | |
| SCHEMBL8621210 | 0.76 | PPARA (0.48) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL9702017 | 0.75 | PPARA (0.55) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8050263 | 0.73 | PPARA (0.65) | PPARAPPARGTTRCYP1A2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | disclosed |
| EP-0763527-A1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-03-19 | — | — | EP | disclosed |