SCHEMBL8767488

SCHEMBL8767488

CC(=O)Oc1c(C)cc(OCCc2ccc(OC(C)(C)C(=O)O)cc2)c(C)c1C

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.57
PPARD Q03181 14/20 0.57
PPARG P37231 13/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8924023 0.89 PPARA (0.46) PPARAPPARDPPARG
SCHEMBL8768731 0.85 PPARA (0.62) PPARAPPARDPPARG
SCHEMBL8050816 0.84 PPARA (0.48) PPARAPPARDPPARG
SCHEMBL8616248 0.78 PPARG (0.38) PPARAPPARDPPARG
SCHEMBL7096822 0.70 HTT (0.45)
SCHEMBL14584458 0.70 PPARG (0.81) PPARAPPARDPPARG
SCHEMBL28763057 0.70 PPARG (0.71) PPARAPPARDPPARG
SCHEMBL8924029 0.70 PPARG (0.64) PPARAPPARDPPARG
SCHEMBL8616686 0.70 PPARA (0.51) PPARAPPARDPPARG
SCHEMBL27674848 0.69 PPARG (0.70) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP disclosed
EP-0621255-A1 Substituted phenoxy-isobutyric acids and esters ADIR ET COMPAGNIE (FR) 1994-10-26 EP disclosed