Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050816 | 0.89 | PPARA (0.48) | PPARGPPARAPPARDTTRCYP1A2 | |
| SCHEMBL8924023 | 0.85 | PPARA (0.46) | PPARGPPARAPPARDCYP1A2TSHR | |
| SCHEMBL8767488 | 0.78 | PPARA (0.57) | PPARGPPARAPPARD | |
| SCHEMBL8617055 | 0.77 | CYP4F2 (0.52) | PPARASMN1; SMN2SLCO1B3SLCO1B1S1PR1 | |
| SCHEMBL8616686 | 0.76 | PPARA (0.51) | PPARGPPARAPPARDTTRCYP1A2 | |
| SCHEMBL8624692 | 0.76 | PPARA (0.45) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL10459179 | 0.76 | S1PR1 (0.46) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL10459075 | 0.72 | L3MBTL1 (0.59) | PPARACYP4F2CYP4A11 | |
| SCHEMBL8051214 | 0.72 | PPARA (0.51) | PPARGPPARAPPARDTTRCYP1A2 | |
| SCHEMBL5892307 | 0.70 | PPARA (0.49) | PPARACYP1A2TSHRSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |