Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922426 | 0.83 | PKM (0.40) | ALDH1A1PKMNPSR1MAPTMAPK1 | |
| SCHEMBL8919153 | 0.79 | ALDH1A1 (0.39) | ALDH1A1PKMMAPTMAPK1GAA | |
| SCHEMBL8920797 | 0.79 | ALDH1A1 (0.36) | ALDH1A1PKMNPSR1MAPTMAPK1 | |
| SCHEMBL1073892 | 0.79 | PKM (0.44) | ALDH1A1PKMNPSR1MAPTMAPK1 | |
| SCHEMBL14357647 | 0.77 | MAPT (0.48) | ALDH1A1PKMNPSR1MAPTMAPK1 | |
| SCHEMBL5423046 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTGAALMNANPC1 | |
| SCHEMBL1028661 | 0.75 | KDM4E (0.48) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL8922319 | 0.72 | MAPT (0.43) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL5409719 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1MAPTGAASMN1; SMN2POLB | |
| SCHEMBL14401656 | 0.67 | POLB (0.36) | SMN1; SMN2LMNAPOLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663366-A | Process for the synthesis of 4,5-diaminopyrazole derivatives useful for dyeing hair | WELLA AKTIENGESELLSCHAT (DE) | 1997-09-02 | — | — | US | disclosed |