Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924209 | 1.00 | PTGS1 (0.50) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL6447825 | 0.78 | LMNA (0.52) | EPHX1TSHRALDH1A1POLBLMNA | |
| SCHEMBL24168053 | 0.77 | EPHX1 (0.51) | EPHX1ALDH1A1POLBLMNAGAA | |
| SCHEMBL7100552 | 0.76 | PTGS1 (0.51) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL5131364 | 0.75 | PTGS1 (0.53) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL8414651 | 0.74 | PTGS1 (0.55) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL8414650 | 0.74 | PTGS1 (0.55) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL7431544 | 0.74 | MAPT (0.55) | TSHRALDH1A1POLBLMNAMAPT | |
| SCHEMBL8417619 | 0.74 | PTGS1 (0.55) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 | |
| SCHEMBL8417618 | 0.74 | PTGS1 (0.55) | PTGS1PTGS2MT-CO1MT-CO2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011215-A1 | NON-STEROID ANDROGEN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1995-04-27 | — | — | WO | claimed |
| US-5677336-A | ADMINISTERING TO MAMMALS TO MODULATE PROCESSES MEDIATED BY ANDROGEN RECEPTOR | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1995011215-A1 | NON-STEROID ANDROGEN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1995-04-27 | — | — | WO | disclosed |