Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 7/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323576 | 0.84 | L3MBTL1 (0.54) | KMT2AMEN1ALDH1A1PARP1PARP10 | |
| SCHEMBL28050059 | 0.82 | GSK3B (0.55) | KMT2AMEN1GSK3BPTPN1ALDH1A1 | |
| SCHEMBL895690 | 0.82 | MEN1 (0.63) | KMT2AMEN1ALDH1A1PARP1PARP10 | |
| SCHEMBL5628492 | 0.81 | HDAC3 (0.57) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1185244 | 0.80 | KMT2A (0.58) | KMT2AMEN1PARP1PARP10PARP15 | |
| SCHEMBL6930688 | 0.80 | KMT2A (0.62) | KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2546537 | 0.80 | MEN1 (0.61) | KMT2AMEN1ALDH1A1PARP1PARP10 | |
| SCHEMBL6189469 | 0.79 | KCNK3 (0.69) | KMT2AMEN1GSK3BPTPN1PARP1 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.79 | KMT2A (0.57) | KMT2AMEN1PARP1PARP10PARP15 | |
| Hydrochloric Acid SCHEMBL29568124 | 0.79 | KMT2A (0.57) | KMT2AMEN1PARP1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |