Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.48 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708325 | 0.88 | L3MBTL1 (0.59) | L3MBTL1TDP1MEN1KMT2ALMNA | |
| SCHEMBL2927912 | 0.88 | L3MBTL1 (1.00) | L3MBTL1TDP1LMNACES2CES1 | |
| SCHEMBL6803687 | 0.82 | SLC6A2 (0.58) | L3MBTL1TDP1MEN1KMT2ASLC6A2 | |
| Biphenyl SCHEMBL28656314 | 0.82 | L3MBTL1 (0.87) | L3MBTL1TDP1LMNACES2CES1 | |
| SCHEMBL7402172 | 0.82 | L3MBTL1 (0.51) | L3MBTL1TDP1MEN1KMT2ALMNA | |
| SCHEMBL2524805 | 0.81 | LMNA (0.74) | L3MBTL1TDP1MEN1KMT2ASLC6A2 | |
| SCHEMBL8101551 | 0.79 | MEN1 (0.52) | L3MBTL1TDP1MEN1KMT2ASLC6A2 | |
| SCHEMBL14519367 | 0.79 | MEN1 (0.52) | L3MBTL1TDP1MEN1KMT2ASLC6A2 | |
| SCHEMBL3115655 | 0.79 | MEN1 (0.52) | L3MBTL1TDP1MEN1KMT2ASLC6A2 | |
| SCHEMBL14519387 | 0.79 | L3MBTL1 (0.49) | L3MBTL1TDP1MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727998-A4 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0727998-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013067-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-18 | — | — | WO | disclosed |