Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924549 | 0.81 | KDM4E (0.42) | ALDH1A1LMNAP4HTMHSD17B10 | |
| SCHEMBL5263376 | 0.76 | — | — | |
| SCHEMBL9050336 | 0.73 | KDM4E (0.33) | — | |
| SCHEMBL4151368 | 0.73 | FFAR1 (0.54) | KEAP1FFAR1TBXAS1 | |
| SCHEMBL293923 | 0.72 | — | — | |
| SCHEMBL18787310 | 0.72 | — | — | |
| SCHEMBL28312719 | 0.72 | LMNA (0.39) | ALDH1A1LMNA | |
| SCHEMBL8922169 | 0.71 | LMNA (0.40) | ALDH1A1LMNASHMT2 | |
| SCHEMBL241757 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KEAP1FFAR1LMNAP4HTM | |
| SCHEMBL5387075 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |