Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.53 |
| ▸ | ICMT | O60725 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926140 | 0.89 | PLA2G2A (0.53) | PLA2G2AICMT | |
| SCHEMBL8926985 | 0.85 | PLA2G2A (0.60) | PLA2G2AICMT | |
| SCHEMBL8924465 | 0.76 | PLA2G2A (0.60) | PLA2G2AICMT | |
| SCHEMBL8926514 | 0.74 | PLA2G2A (0.63) | PLA2G2AICMT | |
| SCHEMBL8924727 | 0.72 | PLA2G2A (0.56) | PLA2G2AICMT | |
| SCHEMBL8924302 | 0.71 | PLA2G2A (0.68) | PLA2G2AICMT | |
| SCHEMBL7965222 | 0.71 | PLA2G2A (0.81) | PLA2G2AICMT | |
| SCHEMBL8289938 | 0.70 | PLA2G2A (0.74) | PLA2G2AICMTALDH1A1LMNA | |
| SCHEMBL7965309 | 0.70 | PLA2G2A (1.00) | PLA2G2AICMT | |
| SCHEMBL8926099 | 0.70 | PLA2G2A (0.58) | PLA2G2AICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684034-A | INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE | ELI LILLY AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |