SCHEMBL8924897

SCHEMBL8924897

CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)[C@@](O)(C(C)=O)[C@@]1(O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
ALB P02768 1/20 0.42
POLB P06746 1/20 0.42
ADRA1A P35348 1/20 0.42
BLM P54132 1/20 0.42
TK1 P04183 5/20 0.40
TYMP P19971 1/20 0.38
ABCG2 Q9UNQ0 3/20 0.38
ABCB1 P08183 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31084248 0.91 TK1 (0.40) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL6220748 0.81 P2RY2 (0.43) LMNA
SCHEMBL4269958 0.79 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL4261514 0.79 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL4273602 0.79 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL4263186 0.79 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL4259801 0.79 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL9084280 0.79 TK1 (0.46) TK1ABCG2ABCB1
SCHEMBL8103389 0.79 POLA1 (0.30)
SCHEMBL8424715 0.78 ALDH1A1 (0.42) ALDH1A1LMNAALBPOLBADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5625057-A ANTIVIRAL AJINOMOTO CO., INC. (JP) 1997-04-29 US disclosed
EP-0519464-B1 Nucleoside derivatives and production thereof AJINOMOTO KK (JP) 1995-12-20 EP disclosed
EP-0519464-A1 Nucleoside derivatives and production thereof Ajinomoto Co., Inc. (JP) 1992-12-23 EP disclosed