Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996526 | 0.81 | GAA (0.43) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL1023866 | 0.81 | MAPT (0.43) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL14944036 | 0.78 | BRD4 (0.46) | ALDH1A1HPGDKMT2AKDM4EGAA | |
| SCHEMBL10429727 | 0.74 | NPC1 (0.51) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL10503709 | 0.74 | LMNA (0.47) | NPC1RAB9AALDH1A1KMT2AKDM4E | |
| SCHEMBL14994888 | 0.72 | HTR2C (0.35) | KMT2AMEN1ADORA2B | |
| SCHEMBL4378111 | 0.71 | RAB9A (0.51) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL10429700 | 0.68 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL11436206 | 0.68 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL4309468 | 0.68 | MEN1 (0.58) | NPC1RAB9AALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663365-A | Process for the preparation of pyrazolones | JAPAN HYDRAZINE CO., LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0170861-B1 | 3-AMINOCARBONYLMETHOXY-5-PHENYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-4695566-A | 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic compositions containing them, and intermediates in their preparation | KALI-CHEMIE PHARMA GMBH (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |
| EP-0170861-A1 | 3-Aminocarbonylmethoxy-5-phenylpyrazole compounds, process for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1986-02-12 | — | — | EP | disclosed |