Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925237 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL27335524 | 0.76 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8440038 | 0.72 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7984467 | 0.70 | PTGS2 (0.62) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL8654540 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL10073203 | 0.68 | PTGS2 (0.64) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL8094206 | 0.67 | PTGS2 (0.51) | PTGS2PTGS1ADORA2AADORA1KDM4E | |
| SCHEMBL7466367 | 0.67 | PTGS2 (0.55) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL6725632 | 0.66 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6101739 | 0.66 | PTGS2 (0.59) | PTGS2PTGS1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |