Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.53 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925463 | 0.83 | MAP2K4 (0.43) | PTGS2PTGS1MAP2K4 | |
| SCHEMBL8925263 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL6180483 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8766048 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5078441 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL4212020 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8073634 | 0.77 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7088302 | 0.75 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8926255 | 0.74 | PSD (0.47) | PTGS2CA12CA2CA9 | |
| SCHEMBL8925320 | 0.74 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |