Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19453101 | 0.98 | ALOX5 (0.36) | ALOX5GAAFAAHMGLLMEN1 | |
| SCHEMBL19918777 | 0.94 | MITF (0.33) | ALOX5GAAMEN1KMT2ATDP1 | |
| SCHEMBL19918798 | 0.94 | ALOX5 (0.41) | ALOX5GAAFAAHMGLLCCR2 | |
| SCHEMBL24409413 | 0.94 | ALOX5 (0.41) | ALOX5GAAFAAHMGLLCCR2 | |
| SCHEMBL11028833 | 0.92 | ALOX5 (0.38) | ALOX5GAAFAAHMGLLCCR2 | |
| SCHEMBL19918839 | 0.87 | BRD4 (0.36) | ALOX5FAAHMGLLKMT2A | |
| SCHEMBL19478707 | 0.86 | ALOX5 (0.36) | ALOX5GAAFAAHMGLLMEN1 | |
| SCHEMBL18799321 | 0.85 | BRD4 (0.33) | L3MBTL1MITFSMN1; SMN2 | |
| SCHEMBL21602285 | 0.84 | ALOX5 (0.36) | ALOX5GAAFAAHMGLLMEN1 | |
| SCHEMBL19478690 | 0.83 | ALOX5 (0.35) | ALOX5GAAFAAHMGLLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702716-A | CONTROLLED RELEASE IMPLANT COMPRISING SOLID MICROPOROUS MATRIX OF BIODEGRADABLE THERMOPLASTIC POLYMER WHICH IS INSOLUBLE IN AQUEOUS FLUIDS, BIOLOGICALLY ACTIVE AGENT, WATER INSOLUBLE RATE RETARDING AGENT | ATRIX LABORATORIES, INC. (US) | 1997-12-30 | — | — | US | claimed |