SCHEMBL19918798

SCHEMBL19918798

CCCCCCC(C)(C)N1CCCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
CCR2 P41597 3/20 0.34
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CXCR4 P61073 1/20 0.34
GAA P10253 1/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
PIK3CD O00329 1/20 0.33
LMNA P02545 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24409413 1.00 ALOX5 (0.41) ALOX5FAAHMGLLBRD4BRD2
SCHEMBL11028833 0.98 ALOX5 (0.38) ALOX5FAAHMGLLBRD4BRD2
SCHEMBL19453101 0.95 ALOX5 (0.36) ALOX5FAAHMGLLCCR2CCR1
SCHEMBL8925332 0.94 ALOX5 (0.36) ALOX5FAAHMGLLCCR2CCR1
SCHEMBL19918839 0.93 BRD4 (0.36) ALOX5FAAHMGLLBRD4BRD2
SCHEMBL21922559 0.87 ALOX5 (0.41) ALOX5FAAHMGLLBRD4BRD2
SCHEMBL19918777 0.87 MITF (0.33) ALOX5BRD4BRD2GAAALDH1A1
SCHEMBL18799294 0.87 ALOX5 (0.41) ALOX5FAAHMGLLBRD4BRD2
SCHEMBL19918791 0.86 BRD4 (0.39) ALOX5BRD4BRD2PIK3CDLMNA
SCHEMBL26946782 0.85 ALOX5 (0.40) ALOX5FAAHMGLLBRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-11076594-B2 Pyrazolone compound or salt thereof, preparation method therefor, herbicide composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUNDS CO., LTD. (CN) 2021-08-03 US disclosed
US-20180055054-A1 PYRAZOLONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, HERBICIDE COMPOSITION AND USE THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUNDS CO., LTD. (CN) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS ALOX5 3201/4885FAAH 840/4885MGLL 2179/4885
US-20180055054-A1 PYRAZOLONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, HERBICIDE COMPOSITION AND USE THEREOF THEM6, NOTUM, CYP4F11 ALOX5 2408/4885FAAH 2133/4885MGLL 3462/4885
US-11076594-B2 Pyrazolone compound or salt thereof, preparation method therefor, herbicide composition and use thereof THEM6, NOTUM, CYP4F11 ALOX5 2408/4885FAAH 2133/4885MGLL 3462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.