Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925237 | 0.83 | PTGS2 (0.54) | MAP2K4PTGS1PTGS2 | |
| SCHEMBL8195709 | 0.77 | GSK3B (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8188505 | 0.74 | KDM4E (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8925681 | 0.72 | GSK3B (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8637993 | 0.72 | RXFP1 (0.34) | KMT2AMAPTHTTPTGS2ALOX5 | |
| SCHEMBL8196657 | 0.68 | MAPK14 (0.34) | KDM4ERAB9APTGS1PTGS2ALOX5 | |
| SCHEMBL8953683 | 0.68 | ENPP1 (0.41) | MEN1KMT2ANPSR1SMN1; SMN2LMNA | |
| SCHEMBL5203034 | 0.67 | PTGS2 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3464473 | 0.66 | MEN1 (0.51) | MAPK1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10731646 | 0.65 | MLYCD (0.52) | MAP2K4GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |