Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926419 | 0.87 | ACHE (0.41) | SRD5A2ACHE | |
| SCHEMBL8927216 | 0.84 | SRD5A2 (0.34) | SRD5A2G6PDACHE | |
| SCHEMBL8926272 | 0.80 | NR1H4 (0.37) | SRD5A2HTTACHENR1H4 | |
| SCHEMBL8925509 | 0.79 | SRD5A1 (0.52) | SRD5A2 | |
| SCHEMBL8926795 | 0.78 | NR1H4 (0.36) | SRD5A2HTTACHENR1H4 | |
| SCHEMBL8926937 | 0.77 | SRD5A2 (0.38) | SRD5A2G6PD | |
| SCHEMBL8925996 | 0.76 | ALDH1A1 (0.37) | SRD5A2ACHE | |
| SCHEMBL8927056 | 0.73 | SRD5A2 (0.33) | SRD5A2 | |
| SCHEMBL8726903 | 0.72 | SRD5A1 (0.43) | SRD5A2EPHX2 | |
| SCHEMBL8726908 | 0.72 | SRD5A1 (0.43) | SRD5A2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |