SCHEMBL3462397

SCHEMBL3462397

C[SiH](C)O[Si](C)(C)CCCOc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.55
PPARA Q07869 3/20 0.55
L3MBTL1 Q9Y468 4/20 0.51
LMNA P02545 3/20 0.51
MAPT P10636 2/20 0.51
MAPK1 P28482 1/20 0.50
PPARG P37231 3/20 0.48
PPARD Q03181 1/20 0.48
PKM P14618 1/20 0.48
KDM4E B2RXH2 3/20 0.47
HRH4 Q9H3N8 1/20 0.47
LTA4H P09960 1/20 0.47
LSS P48449 2/20 0.46
ALDH1A1 P00352 3/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927099 0.89 TSHR (0.55) L3MBTL1MAPK1PKMALDH1A1HTT
SCHEMBL14012499 0.84 GAA (0.57) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL12974381 0.83 GAA (0.64) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL14012502 0.82 GAA (0.55) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL1255310 0.81 GAA (0.60) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL8647078 0.81 GAA (0.60) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL17732445 0.80 GAA (0.59) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL8925519 0.79 LMNA (0.48) LMNAMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL8646278 0.78 GAA (0.57) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL2798805 0.78 L3MBTL1 (0.63) GAAPPARAL3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799884-B2 Polymeric photoinitiators HENKEL AG & CO. KGAA (DE) 2010-09-21 US disclosed
US-7795364-B2 Polymeric photoinitiators HENKEL AG & CO. KGAA (DE) 2010-09-14 US disclosed
US-7745505-B2 Polymerizable photoinitiator with a spacer containing both ethylene oxide directly bonded to the chromophore (e.g., benzophenone) and urethane, urea, or disiloxane group closely linked to the unsaturaturated group, e.g., a styrenic couble bond HENKEL AG & CO. KGAA (DE) 2010-06-29 US disclosed
EP-1519964-B1 POLYMERIC PHOTOINITIATORS NAT STARCH CHEM INVEST (US) 2009-02-18 EP disclosed
US-20070208099-A1 Amide linked maleinized addition polymer, especially a diene polymer, reacted with an aminated benzophenone, benzil, thioxanthone, 2,3-norboradione, anthraquinone, coumarone, or 3-carbonylcoumarone; UV curable adhesives, coatings, encapsulants; thiol-ene photocurable compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2007-09-06 US disclosed
US-20070078246-A1 Type II H-extraction; mercapto-functional benzophenone-type chromophore bound to butadiene/styrene rubber so it does not remain in final odorless product; UV radiation curable hot melt pressure sensitive adhesive; photocurable composition with multifunctional thiol crosslinker and a polyene; thiol-ene NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2007-04-05 US disclosed
US-7157535-B2 Polymeric photoinitiators NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-01-02 US disclosed
EP-1676870-A1 Photoinitiators and uv-crosslinkable acrylic polymers for pressure sensitive adhesives National Starch and Chemical Investment Holding Corporation (US) 2006-07-05 EP disclosed
US-20060142408-A1 Polymerizable photoinitiator with a spacer containing both ethylene oxide directly bonded to the chromophore (e.g., benzophenone) and urethane, urea, or disiloxane group closely linked to the unsaturaturated group, e.g., a styrenic couble bond NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2006-06-29 US disclosed