Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925534 | 1.00 | FAAH (0.46) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL7663609 | 0.84 | CYP2C9 (0.44) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL7752227 | 0.84 | FAAH (0.46) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL9047024 | 0.83 | FPR2 (0.44) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL9047032 | 0.83 | FPR2 (0.44) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL1747766 | 0.82 | ALDH1A1 (0.40) | FAAHCYP2C9CHRNB2CHRNA4MAPT | |
| SCHEMBL1747764 | 0.82 | ALDH1A1 (0.40) | FAAHCYP2C9CHRNB2CHRNA4MAPT | |
| SCHEMBL1747765 | 0.82 | ALDH1A1 (0.40) | FAAHCYP2C9CHRNB2CHRNA4MAPT | |
| SCHEMBL7664009 | 0.82 | FAAH (0.44) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 | |
| SCHEMBL7664002 | 0.82 | FAAH (0.44) | FAAHCYP2C9NAMPTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304566-A | Pyridine compounds which have useful insecticidal utility | NIPPON SODA CO., LTD (JP) | 1994-04-19 | — | — | US | claimed |
| US-5612358-A | Pyridine compouds which have useful insecticidal activity | NIPPON SODA CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| US-5304566-A | Pyridine compounds which have useful insecticidal utility | NIPPON SODA CO., LTD (JP) | 1994-04-19 | — | — | US | disclosed |
| WO-1991004965-A1 | AMINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1991-04-18 | — | — | WO | disclosed |