Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | HTR6 | P50406 | 2/20 | 0.69 |
| ▸ | HTR2C | P28335 | 2/20 | 0.69 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.69 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | MARK3 | P27448 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.55 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ru-24969 SCHEMBL2359264 | 0.82 | HTR6 (1.00) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| Ru-24969 SCHEMBL29390076 | 0.82 | HTR6 (1.00) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5705100 | 0.80 | KDM4E (0.66) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8125400 | 0.79 | KDM4E (0.58) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30909308 | 0.78 | KDM4E (0.53) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7485622 | 0.78 | KDM4E (0.53) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16801767 | 0.77 | KDM4E (0.56) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| Ru-24969 SCHEMBL29550112 | 0.76 | HTR6 (0.81) | HTR1DMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6541377 | 0.76 | HTR2C (0.47) | KDM4EALDH1A1CYP1A2CYP3A4HTR2C | |
| SCHEMBL6631651 | 0.76 | KDM4E (0.70) | HTR1DMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639752-A | SEROTONIN AGONIST | PFIZER INC (US) | 1997-06-17 | — | — | US | disclosed |