Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485622 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL8925573 | 0.78 | HTR1D (0.69) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL7483889 | 0.78 | HTR1A (0.53) | KDM4EHSD17B10KMT2AHTR6HTR2C | |
| SCHEMBL30908991 | 0.78 | HTR1A (0.53) | KDM4EHSD17B10KMT2AHTR6HTR2C | |
| SCHEMBL8558613 | 0.76 | HTR6 (0.65) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL6631360 | 0.75 | HTR6 (0.60) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL9764393 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL27913517 | 0.71 | KMT2A (0.78) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL8820109 | 0.71 | HSD17B10 (0.56) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL5705100 | 0.70 | KDM4E (0.66) | KDM4EALDH1A1MAPTHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |