Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927370 | 0.91 | TSHR (0.42) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL875892 | 0.91 | TSHR (0.48) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL1180790 | 0.91 | TSHR (0.48) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8926570 | 0.86 | TSHR (0.45) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8926544 | 0.85 | ALDH1A1 (0.50) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8927396 | 0.84 | ALDH1A1 (0.58) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8927394 | 0.84 | ALDH1A1 (0.58) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8927116 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8926884 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1FASNFAAHKDM4E | |
| SCHEMBL8925447 | 0.83 | TSHR (0.33) | TSHRALDH1A1FAAHLPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5600034-A | HEAT TREATING DIALLYL ETHERS IN PRESENCE OF CATALYST CONTAINING PALLADIUM AND PHOSPHORUS COMPOUNDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-02-04 | — | — | US | disclosed |