Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Anthracene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mequinol SCHEMBL9484363 | 0.86 | LTA4H (0.70) | ESR2LTA4HAPPCALM1GAA | |
| Mequinol SCHEMBL8923815 | 0.86 | CYP2A6 (0.52) | ESR2LTA4HCYP1A2CYP2A6APP | |
| Mequinol SCHEMBL1535640 | 0.85 | ESR2 (0.84) | ESR2LTA4HAPPCALM1GAA | |
| 1,4-Dimethoxybenzene SCHEMBL8351066 | 0.85 | ESR2 (0.84) | ESR2LTA4HAPPCALM1GAA | |
| Mequinol SCHEMBL21009 | 0.85 | — | — | |
| Mequinol SCHEMBL166535 | 0.85 | ESR2 (0.84) | ESR2LTA4HAPPCALM1GAA | |
| Mequinol SCHEMBL8924974 | 0.84 | CYP1A2 (0.49) | ESR2LTA4HCYP1A2CYP2A6APP | |
| Mequinol SCHEMBL8167563 | 0.84 | LTA4H (0.67) | ESR2LTA4HCYP1A2APPCALM1 | |
| 1,4-Dimethoxybenzene SCHEMBL27700751 | 0.83 | LTA4H (0.65) | ESR2LTA4HAPPCALM1GAA | |
| Mequinol SCHEMBL10589275 | 0.83 | LTA4H (0.46) | ESR2LTA4HCYP1A2CYP2A6APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663032-A | NAPHTHOL DERIVATIVE REDUCING AGENT | CANON KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0332455-B1 | Photosensitive material and image forming method | CANON KK (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0653680-A2 | Photosensitive composition, photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1995-05-17 | — | — | EP | disclosed |
| US-5041369-A | Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye | CANON KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0332455-A2 | Photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0326424-A2 | Photosensitive composition, photosensitive material, and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-08-02 | — | — | EP | disclosed |