Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527259 | 0.93 | BCAT1 (0.39) | PPOXL3MBTL1RHEBPTGER1MAPK14 | |
| SCHEMBL10575906 | 0.92 | PPOX (0.35) | PPOXL3MBTL1RHEBPTGER1MEN1 | |
| SCHEMBL10572280 | 0.92 | MAPK14 (0.40) | PPOXPTGER1MAPK14BCAT1BCAT2 | |
| SCHEMBL10577200 | 0.91 | PPOX (0.49) | PPOXMAPK14MEN1KMT2AMRGPRX4 | |
| SCHEMBL7237202 | 0.91 | TRIM24 (0.39) | PPOXL3MBTL1PTGER1MEN1KMT2A | |
| SCHEMBL10574950 | 0.90 | SCN9A (0.40) | PPOXMAPK14MEN1KMT2ABCAT1 | |
| SCHEMBL10578510 | 0.89 | RXRA (0.40) | PPOXPTGER1MRGPRX4 | |
| SCHEMBL10574064 | 0.89 | MAOB (0.37) | PPOXMEN1KMT2ABCAT1BCAT2 | |
| SCHEMBL7227825 | 0.89 | TRIM24 (0.40) | PPOXMAPK14BCAT1BCAT2 | |
| SCHEMBL10574477 | 0.89 | NPC1 (0.39) | PPOXMAPK14MEN1KMT2ABCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| US-5602077-A | CONTROLLING GROWTH OF UNDESIRED VEGETATION IN PLANTATION CROPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| US-5567670-A | TETRAHYDROTRIAZINE-DIONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| WO-1993014073-A1 | PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |