Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863912 | 0.74 | KDM4E (0.45) | KDM4EPOLBMEN1KMT2ALMNA | |
| SCHEMBL8070606 | 0.74 | IMPDH2 (0.36) | KDM4EPOLBMEN1KMT2AHSD17B10 | |
| SCHEMBL8924385 | 0.74 | MEN1 (0.34) | KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL6773536 | 0.73 | KDM4E (0.33) | KDM4EPOLB | |
| SCHEMBL8600805 | 0.72 | HTT (0.44) | KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8603161 | 0.71 | KDM4E (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL9507056 | 0.69 | LMNA (0.44) | KDM4EPOLBLMNATSHRHSD17B10 | |
| SCHEMBL13134484 | 0.67 | LMNA (0.42) | KDM4EPOLBLMNATSHRHSD17B10 | |
| SCHEMBL9786758 | 0.66 | IMPDH2 (0.36) | KDM4EPOLBHSD17B10 | |
| SCHEMBL28158529 | 0.66 | TSHR (0.37) | KDM4EPOLBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |