Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070606 | 0.81 | IMPDH2 (0.36) | MEN1KMT2APDE4APDE3ACA2 | |
| SCHEMBL8926062 | 0.74 | KDM4E (0.33) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9507056 | 0.72 | LMNA (0.44) | CA2KDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL13134484 | 0.70 | LMNA (0.42) | CA2KDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL5865884 | 0.67 | LMNA (0.44) | CA2KDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL8843086 | 0.67 | PDE4A (0.38) | MEN1KMT2APDE4APDE3ACA2 | |
| SCHEMBL11713115 | 0.66 | — | — | |
| SCHEMBL10383779 | 0.66 | CA2 (0.35) | MEN1KMT2ACA2KDM4EALDH1A1 | |
| SCHEMBL9786758 | 0.66 | IMPDH2 (0.36) | CA2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13660538 | 0.65 | MAOB (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |