Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126611 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8924469 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8924250 | 0.73 | KCNA5 (0.44) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7649974 | 0.70 | MAPK10 (0.55) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7655539 | 0.69 | LMNA (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL17522756 | 0.69 | MAPT (0.53) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10084475 | 0.69 | HSD17B10 (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8922778 | 0.68 | PARG (0.45) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL31161048 | 0.68 | CA9 (0.55) | ALDH1A1KMT2AMEN1XDHPOLB | |
| SCHEMBL31160820 | 0.68 | KMT2A (0.53) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693637-A | Bicycle derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |