Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490333 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL30072440 | 0.69 | MEN1 (0.48) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL18956900 | 0.69 | MEN1 (0.48) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL7495956 | 0.67 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL1428159 | 0.67 | TXNRD1 (0.58) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL5205562 | 0.67 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL25133344 | 0.66 | TXNRD1 (0.38) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL30720926 | 0.66 | TXNRD1 (0.38) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL3143317 | 0.66 | CYP3A4 (0.40) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL7836090 | 0.66 | TXNRD1 (0.56) | S1PR4MAPTS1PR1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698584-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1997-12-16 | — | — | US | disclosed |