Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283734 | 0.91 | ESR1 (0.34) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL11783321 | 0.88 | CYP2C9 (0.41) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL9155526 | 0.86 | CNR1 (0.43) | CYP3A4PTGS2CNR1CNR2 | |
| SCHEMBL1835827 | 0.85 | CNR2 (0.38) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL11661752 | 0.85 | ALDH1A1 (0.56) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL10885993 | 0.84 | CNR1 (0.45) | CYP3A4PTGS2CNR1CNR2 | |
| SCHEMBL11661680 | 0.83 | HSPA5 (0.42) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL8335913 | 0.83 | LMNA (0.36) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL9817596 | 0.83 | HSPA5 (0.50) | CA2CA1ESR1ESR2ALDH1A1 | |
| SCHEMBL9188294 | 0.82 | CA2 (0.41) | CA2CA1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-5702855-A | Electrophotographic photoconductor containing a mixture of a phenol compound and an organic sulfur-containing compound | RICOH COMPANY, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |