Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383256 | 0.73 | GPR84 (0.50) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5172958 | 0.73 | GPR84 (0.50) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL772622 | 0.73 | GPR84 (0.50) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8208352 | 0.72 | HTR1D (0.40) | MAPTHTR6SMN1; SMN2 | |
| SCHEMBL8507170 | 0.72 | HTR1D (0.43) | HTR6 | |
| SCHEMBL9287650 | 0.71 | HTR1D (0.42) | HTR6CYP2C19 | |
| SCHEMBL8209090 | 0.71 | SLC6A4 (0.50) | — | |
| SCHEMBL8209129 | 0.71 | SLC6A4 (0.43) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL9287655 | 0.71 | HTR1D (0.42) | HTR6CYP2C19 | |
| SCHEMBL774639 | 0.71 | SLC6A4 (0.43) | ALDH1A1GAAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639752-A | SEROTONIN AGONIST | PFIZER INC (US) | 1997-06-17 | — | — | US | disclosed |